top of page
![](https://static.wixstatic.com/media/6218a6_41bca9673bd84eec8b44272a4bb40187~mv2_d_2400_1664_s_2.png/v1/fill/w_96,h_67,al_c,q_85,usm_0.66_1.00_0.01,blur_2,enc_auto/6218a6_41bca9673bd84eec8b44272a4bb40187~mv2_d_2400_1664_s_2.png)
History
HISTORY OF DRUG DELIVERY
From oral medication to the modern transdermal delivery system
Drug Formulation
SmithKline Beecham developed the first sustained drug formulation.
1940s-1955
Dissolution
Dissolution-controlled release mechanism becomes most widely used delivery method
1955-1970s
Peptides/Proteins
Biodegradable poly(lactic-co-glycolic acid) (PLGA) was designed for elongated delivery of peptide and protein drugs.
1970s-1985
Hydrogels
Environmentally-sensitive Hydrogels were designed with self-regulated release abilities
1985-2000s
Polymers
Smart polymers have signal specificity and sensitivity.
2000s-2010
Graphene Patch
Present day graphene patches incorporates gold meshes for sensing and electrosensitive response. Surface microneedles provide noninvasive drug delivery.
2010-present
![01.png](https://static.wixstatic.com/media/6218a6_f426a8f6213e46febd32e557c37f10f9~mv2.png/v1/fill/w_78,h_42,al_c,q_85,usm_0.66_1.00_0.01,blur_2,enc_auto/01.png)
![SmithKline Beecham.jpg](https://static.wixstatic.com/media/6218a6_cb2c3f8736c34a8daf40f69175f5a68e~mv2.jpg/v1/crop/x_0,y_105,w_300,h_118/fill/w_300,h_118,al_c,q_80,enc_auto/SmithKline%20Beecham.jpg)
![dissolution.jpg](https://static.wixstatic.com/media/6218a6_dec91096254b4958870554f021f9ea9b~mv2.jpg/v1/crop/x_0,y_329,w_565,h_220/fill/w_303,h_118,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/dissolution.jpg)
![PLGA drug delivery.png](https://static.wixstatic.com/media/6218a6_4bad163aff7b4cf1bee84adf95f2449f~mv2.png/v1/fill/w_311,h_147,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/PLGA%20drug%20delivery.png)
![1-s2.0-S0014305714004091-gr2.jpg](https://static.wixstatic.com/media/6218a6_bfe55fb126134c879f93079aa3b2bf27~mv2.jpg/v1/crop/x_343,y_0,w_178,h_224/fill/w_178,h_224,al_c,q_80,enc_auto/1-s2_0-S0014305714004091-gr2.jpg)
![smart polymer.jpg](https://static.wixstatic.com/media/6218a6_b2b06d1bd4be4d6e892238d515fc776b~mv2.jpg/v1/fill/w_59,h_42,al_c,q_80,usm_0.66_1.00_0.01,blur_2,enc_auto/smart%20polymer.jpg)
1st Generation
2nd Generation
3rd Generation
bottom of page