top of page
The Problem
The Opioid Epidemic
Opioid overdose
deaths in the US
2.7M
suffered from an opioid
use disorder in 2020
#1
cause of death among
18-45 year-olds in the US
500K
have died from opioid overdose over the past decade
30%
of people who needed treatment received it in 2017
Limited treatment modalities continue to be a significant barrier in the mitigation of opioid use disorder
Limitations of Present Technology
Methadone, Buprenorphine, Naltrexone
Synthetic opioid agonists that bind to opioid receptors and alleviate withdrawal symptoms, prevent drug cravings, and blunt the effects of other opioids
​
Limitations:
-
Inherent risk of abuse
-
Undesired side effects
-
Low patient compliance
-
Lack of accessibility
-
Daily clinic visits required
Naloxone
Opioid overdose-reversal medication, restores normal breathing by binding to opioid receptors and reversing the effects of other opioids in the brain
​
Limitations:
-
Undesirable withdrawal symptoms
-
Must be administered rapidly
-
Often unavailable or administered too late
​
50% of people on current treatment medications relapse within just
6 months
bottom of page