No. Because our vaccine is specially designed to target the structures of only the most commonly abused opioids, it will not interfere with other medications currently used to treat opioid use disorder or to reverse overdose, including methadone, buprenorphine, naltrexone and naloxone.

This vaccine does not interfere with the numerous chemically-different pain medications, such as tramadol, methadone, and non-steroidal anti-inflammatory drugs (NSAIDs).

While this is possible, our target population is patients with opioid use disorder who have intentions to recover and are thereby less likely to engage in such behavior. The vaccine could also be used in combination with medications or cognitive behavioral therapy to prevent such an issue.

Yes. Prophylactic vaccination could offer protection for first responders, law enforcement, or other people who are at high risk for accidental inhalation of potent opioids like fentanyl.