Vaccine Design

Click through the slides to learn about the core components of our vaccine.

Hapten

Molecular antigen that structurally resembles the target drug,

providing a template for the formation of anti-drug antibodies.

We introduce a chemically contiguous hapten that carries dual epitopes to encompass the six target opioids.

Our Epitope #1 Design

Epitope #1

(Morphine, codeine, oxycodone, hydrocodone, heroin):

Morphinan ring scaffold

that is conserved across

the molecular structures

of the opioids

epitope 1.png
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Epitope #2

(Fentanyl):

Modified form of fentanyl that

allows it to closely resemble a

fentanyl molecule without

behaving like it

Our Epitope #2 Design

Our Epitope #2 Design

Put together, our vaccine design looks like this:
Screen Shot 2022-03-17 at 12.39.36 AM.png

Prototype:

syringe.jpg
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