Vaccine Design
Click through the slides to learn about the core components of our vaccine.
Hapten
Molecular antigen that structurally resembles the target drug,
providing a template for the formation of anti-drug antibodies.
We introduce a chemically contiguous hapten that carries dual epitopes to encompass the six target opioids.
Our Epitope #1 Design
Epitope #1
(Morphine, codeine, oxycodone, hydrocodone, heroin):
Morphinan ring scaffold
that is conserved across
the molecular structures
of the opioids
Epitope #2
(Fentanyl):
Modified form of fentanyl that
allows it to closely resemble a
fentanyl molecule without
behaving like it
Our Epitope #2 Design
Our Epitope #2 Design
Put together, our vaccine design looks like this:
Prototype:
