Coronary artery disease (CAD) has affected humans for centuries, with evidence found in ancient Egyptian mummies. Over time, medical discoveries, from Leonardo da Vinci’s observations to 20th-century surgical innovations have advanced our understanding of heart disease. Today, we continue that legacy with cutting-edge solutions like NAPS, designed to target plaque at its source.

1506
Leonardo Da Vinci performs an autopsy discovering narrowed arteries [5]

Medicina Rationalis Systematica
published promoting the nature of heart disease and first medical recognition of CAD [7]
1718



1974
Invention of Angioplasty Procedure [9]
The first IVUS devices invented allowing real time depiction of plaque buildup [11]
1980's
21st Century Nanotechnology Research and Development Act allowed for the advancement of nano-particles in targeted drug delivery [13]

2000's
Discovery of the Circulatory Blood System [6]
1628
1960

First successful Coronary Bypass Graft Surgery [8]
The FDA approves Pulse Electro Magnetic Therapy revolutionizing medical practices and allowing for precise treatment [10]


1979

Introduction of the First Self Expanding coronary stent [12]
1986
Discovery of Quantum Dots further revolutionizes nanotechnology [14]

2023
2035
The NAPS Revolution
Combining nanotechnology with targeted drug delivery for CAD