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References

Websites and Articles

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"Monoclonal Antibody Drugs for Cancer: How They Work." Mayo Clinic. Mayo Foundation for Medical Education and Research, 09 Sept. 2016. Web. 04 Apr. 2018. <https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/monoclonal-antibody/art-20047808>.

"Understanding Targeted Therapy." Cancer.Net, 12 May 2017. Web. 04 Apr. 2018. <https://www.cancer.net/navigating-cancer-care/how-cancer-treated/personalized-and-targeted-therapies/understanding-targeted-therapy>.

"National Comprehensive Cancer Network." Targeted Therapy. Web. 04 Apr. 2018. <https://www.nccn.org/patients/resources/life_with_cancer/treatment/targeted_therapy.aspx>.

"Targeted Cancer Therapies." National Cancer Institute. Web. 04 Apr. 2018. <https://www.cancer.gov/about-cancer/treatment/types/targeted-therapies/targeted-therapies-fact-sheet>.

"Scientists Cure Lupus in Mice with a One-Two Punch." Healthline. Healthline Media,Web. 04 Apr. 2018. <https://www.healthline.com/health-news/scientists-cure-lupus-in-mice-021115>.

"Evolution of Cancer Treatments: Targeted Therapy." American Cancer Society. Web. 04 Apr. 2018. <https://www.cancer.org/cancer/cancer-basics/history-of-cancer/cancer-treatment-targeted-therapy.html>.

Yan, Li, Neal Rosen, and Carlos Arteaga. Chinese Journal of Cancer. Sun Yat-sen University Cancer Center, Jan. 2011. Web. 04 Apr. 2018. <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012258/>.

"The Origins of Metformin." Web. 04 Apr. 2018. <http://www.diabetesforecast.org/2010/dec/the-origins-of-metformin.html>.

"The Louis Sokoloff Papers: Establishing the Foundation for PET Scanning: The 2-Deoxyglucose Method, 1968-1978." U.S. National Library of Medicine. National Institutes of Health, Web. 04 Apr. 2018. <https://profiles.nlm.nih.gov/ps/retrieve/Narrative/NL/p-nid/378>.

"A Phase I/II Trial of 2-Deoxyglucose (2DG) for the Treatment of Advanced Cancer and Hormone Refractory Prostate Cancer - Full Text View." A Phase I/II Trial of 2-Deoxyglucose (2DG) for the Treatment of Advanced Cancer and Hormone Refractory Prostate Cancer - Full Text View - ClinicalTrials.gov. Web. 04 Apr. 2018. <https://clinicaltrials.gov/ct2/show/NCT00633087>.

Singh-Jasuja, H., N. Hilf, H. U. Scherer, D. Arnold-Schild, H. G. Rammensee, R. E. Toes, and H. Schild. "The Heat Shock Protein Gp96: A Receptor-targeted Cross-priming Carrier and Activator of Dendritic Cells." Cell Stress & Chaperones. U.S. National Library of Medicine, Nov. 2000. Web. 04 Apr. 2018. <https://www.ncbi.nlm.nih.gov/pubmed/11189453>.

Han, Jung Min, Nam Hoon Kwon, Jin Young Lee, Seung Jae Jeong, Hee Jung Jung, Hyeong Rae Kim, Zihai Li, and Sunghoon Kim. "Identification of Gp96 as a Novel Target for Treatment of Autoimmune Disease in Mice." PLOS ONE. Public Library of Science, Web. 04 Apr. 2018. <http://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0009792>.

Miceli, M. C., and J. R. Parnes. "The Roles of CD4 and CD8 in T Cell Activation." Seminars in Immunology. U.S. National Library of Medicine, May 1991. Web. 04 Apr. 2018. <https://www.ncbi.nlm.nih.gov/pubmed/1909592>.

Images

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*All images not cited are original.

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*Digital Prototype was student made.

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Nucleus Medical Media, Antibody Immune Response. Web. 02 Apr. 2018. <https://www.youtube.com/watch?v=lrYlZJiuf18>.

Nucleus Medical Media, Lupus. Web. 02 Apr. 2018. <https://www.youtube.com/watch?v=WgfFcpAD9XQ>.

Wilson, Hannah. "Promising Results for First-line Targeted Therapy for Lung Cancer."Oncology Central. Oncology Central, 27 Mar. 2015. Web. 04 Apr. 2018. <https://www.oncology-central.com/2014/12/15/promising-results-for-first-line-targeted-therapy-for-lung-cancer/>.

Dragojevic, Sonja, Jung Su Ryu, and Drazen Raucher. "Polymer-Based Prodrugs: Improving Tumor Targeting and the Solubility of Small Molecule Drugs in Cancer Therapy." MDPI. Multidisciplinary Digital Publishing Institute, 04 Dec. 2015. Web. 04 Apr. 2018. <http://www.mdpi.com/1420-3049/20/12/19804>.

"Immunology and Bipolar Disorder." Bipolar Disorder. N.p., n.d. Web. 06 Apr. 2018. <https://www.gulfbend.org/poc/view_doc.php?type=doc&id=11205&cn=4>.

John Wiley & Sons Ltd. "UCB Lupus Candidate Shows Disease Benefits." UCB Lupus Candidate Shows Disease Benefits | Pharmafile. Web. 04 Apr. 2018. <http://www.pharmafile.com/news/101111/ucb-lupus-candidate-disease>.

Daniel. "2-DeoxyGlucose (2-DG)." Mihaela Catalina Stanciu Foundation for Life. Web. 04 Apr. 2018. <https://www.cancertreatmentsresearch.com/2-deoxyglucose-2-dg/>.

Campbell, Amy. "What to Know About Metformin." Diabetes Self-Management. Web. 04 Apr. 2018. <https://www.diabetesselfmanagement.com/blog/what-to-know-about-metformin/>.

"Admin." Free Clipart Spot. N.p., 23 May 2017. Web. 04 Apr. 2018. <https://freeclipartspot.com/article/top-92-mouse-clipart>.

"Evolution of Cancer Treatments: Targeted Therapy." American Cancer Society. Web. 04 Apr. 2018. <https://www.cancer.org/cancer/cancer-basics/history-of-cancer/cancer-treatment-targeted-therapy.html>.

"American Society of Hematology." Targeted Therapy for Chronic Myeloid Leukemia.16 Feb. 2018. Web. 04 Apr. 2018. <http://www.hematology.org/About/History/50-Years/1529.aspx>.

"Woman Figure Walking in Circles, Human Body..." Woman Figure Walking In Circles, Human Body Temperature, Three Dimensional Human Female Silhouette Isolated On Black Background, 3D Animation Loop Stock Footage Video 34582243 | Shutterstock.Web. 04 Apr. 2018. <https://www.shutterstock.com/video/clip-34582243-stock-footage-woman-figure-walking-in-circles-human-body-temperature-three-dimensional-human-female-silhouette.html>.

"HER2 Signaling Beckons: Dimerization Process, Combination Therapies Highlight New Research." OncLive. Web. 04 Apr. 2018. <http://www.onclive.com/publications/oncology-live/2011/june-2011/her2-signaling-beckons-dimerization-process-combination-therapies-highlight-new-research>.

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