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Background

Throughout medical history, prosthetics have become increasingly intertwined with neuroscience due to the advent of technological advancements. By exploring past discoveries in the fields of neurosurgery and neuroprosthetics, a better understanding of the principles behind N4NO can be acquired.
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1889 |  First wide cranial approach introduced
First intrathecal injection performed  | 1898
1940 |  Advancements in anesthesia and surgical techniques refine craniotomy procedures
Early development of neuroprosthetics and orthotics  | 1950
1980 |   Emergence of nanocarriers in drug delivery research
Pioneering development of noninvasive BCI technology  | 1999
2000 |   Advancements in neuroprosthetics, integrating BCI technology for enhanced control
First successful demonstration of invasive BCI in humans  | 2004
2015 |   Application of nanocarriers in neuromedicine, targeting the blood-brain barrier
 Initial research on neural dust motes and their wireless operation  | 2016
2020 |   Successful implementation of neural dust motes in animal studies
Neuralink's first human patient controls computer mouse through thought  | 2024
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